Research

Meningitis UK's single focus is to develop a vaccine to eradicate meningitis and meningococcal septicaemia through research based exclusively in the UK. Established Research Groups at Institutions across the country are invited to apply for Grant Aid on an annual basis.

Since the charity's inception in 1999, Meningitis UK has invested over £1.5 million into meningitis research projects. Over the next three years we aim to double that figure.

Find out how you can help us achieve our goal

Research in the lab

Why is vaccine research needed?

Meningitis can kill in under 4 hours and is a notoriously difficult disease to diagnose as in the early stages symptoms can appear flu-like, which is why finding a vaccine is so urgent.

Sadly, newspapers report on the pain of families who have suffered from meningitis and its associated diseases almost every day. Official statistics show that there are approximately 2,300 cases of meningitis and meningococcal septicaemia in the UK each year, of which more than 300 will die and hundreds more will be left with permanent disabilities.

Finding a vaccine to prevent all types of meningitis remains one of the biggest challenges to modern medicine. Whilst vaccines exist to protect against certain forms of meningitis, there is still no vaccine to protect against the most common form of bacterial meningitis in the UK - Meningitis B.

The good news is scientists across the UK are working tirelessly to develop a successful vaccine and we are currently involved in funding seven ground breaking vaccine-development projects.

Picture of syringe

Read about our current projects

Why is it so difficult to find a vaccine?

Scientists know that one in 10 people have the meningitis-causing bacteria Neisseria meningitidis living harmlessly in their noses and throats. But what they don't know is why the bacteria sometimes become harmful, spreading to the tissues surrounding the brain causing meningitis and crossing into the bloodstream causing septicaemia.

The search for a vaccine is also complicated because the different meningitis-causing bacteria have different shapes and properties, so a vaccine which can fight one sort, might not be able to fight another. The challenge is to find a vaccine which can stop the spread of the bacteria - no matter what their shape.

What is Meningitis UK's role in funding research?

Meningitis UK is arguably the leading meningitis charity funding vaccine development research undertaken in the UK.

Meningitis UK is a member of the Association of Medical Research Charities (AMRC) the leading umbrella organisation representing medical research charities, who stipulate that member charities must have a clearly defined research strategy and demonstrate good peer review when awarding research grants.

In the UK, a third of research funding is from charities. The combined contribution of AMRC's member charities is greater than that of the Medical Research Council or the Dept. of Health (including the NHS).

Research in the lab

Why Meningitis UK only funds research in the UK

There are many different strains of meningitis and the prominence of the different strains varies from country to country, so while finding a vaccine to eradicate meningitis B in the UK is a priority, it may not be in other countries. By funding research in the UK, we are ensuring that the UK's specific meningitis needs are met.

The knowledge gained through the research we fund is not only moving us closer to finding a vaccine in the UK, but also adding to the global understanding of these bacteria which will hopefully help the fight against theses diseases in all countries.

Meningitis UK's Annual Research Awards

Every year Meningitis UK places an advert in the British Medical Journal inviting established research groups across the UK with a track record in preventative research into meningitis and its associated diseases to apply for a grant to aid existing or new research.

All applications are scrutinised by specially selected international medical experts who act as referees and comment on the scientific merit of the proposed projects. The applications are then reviewed by Meningitis UK's own Scientific Medical Advisory Panel.

Research in the lab

This ensures that only the most worthy research grants are awarded and that priority is given to senior academics in established research groups in the UK who have a track record in research into the prevention of disease caused by meningococcal or pneumococcal infection.

As a condition of funding, researchers must ensure that all useful knowledge acquired from the research is made widely available to further the charity's aim to find a vaccine to eradicate bacterial meningitis and meningococcal septicaemia.

If you are interested in applying for next year's research award round, please visit our Research Grants page

MeningitisUK is the working name of Spencer Dayman MeningitisUK · Registered Charity No.1076774

Spencer Dayman MeningitisUK · Terms & Conditions © Meningitis UK 2005